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Our Science Hub provides you with quick and easy access to all of Physiomics cutting edge research and though leadership, including our latest scientific posters and publications, research papers and webinars.

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Semi-mechanistic efficacy model for PARP + ATR inhibitors…

Publications

A Multiple-Model-Informed Drug-Development Approach for Optimal Regimen Selection…

Publications

Data analysis and model evaluation of chemotherapy induced neutropenia Results from the PARTNER trial

Posters

Physiomics marks record year with expanding consultancy and personalized medicine initiatives

Presentations

Preclinical pharmacokinetic (PK) and tumour growth inhibition (TGI) modelling for mANK-101

Posters

Should personalised dosing have a role in cancer treatment?

Publications

AACR 2023 – Abstract Number: 5699

Presentations

Mathematical modelling in the age of Project Optimus

Webinars

Mathematical modelling in the age of Project Optimus – slides

Presentations

Establishing the preclinical PKPD relationship for NM32-2668 a ROR1 targeting T cell engager

Posters

Establishing the translational PK/PD relationship for BT7480, a Nectin-4/CD137 Bicycle TICA

Posters

The abscopal effect: modeling and predicting the effect of radiation therapy on non-irradiated tumors when combined with immune-checkpoint blockers

Posters

A precision dosing application for patients treated with docetaxel and G-CSF

Posters

Optimizing Dual Immuno-oncology Combinations with a Virtual Tumor

Posters

BioTrinity 2020: Modelling in immuno-oncology

Presentations

Developing a head and neck cancer model to assess the effect of radiotherapy on tumour growth inhibition and regrowth

Posters

Convert Pharmaceuticals Case Study

Case Studies

CellCentric Case Study

Case Studies

Physiomics presentation at Biotrinity 2019

Presentations

Modelling the effect of Radiotherapy on tumour growth inhibition: the head and neck tumour case head and neck tumour case

Posters

A Precision Dosing Application For Advanced Prostate Cancer Chemotherapy

Posters

QSP versus the rest: let the competition commence! by Dr Hitesh Mistry

Publications

A Decision Support System for the treatment of esophageal cancer

Posters

Using Predictive Mathematical Models to Optimise the Scheduling of Anti-Cancer Drugs by David Orrell and Eric Fernandez

Publications

Modelling the Emergence of Resistance to Chemotherapeutics with Virtual Tumour

Posters

Modelling and translating head and neck radiation therapy on all three levels: in vitro, in vivo and clinical

Posters

Virtual Tumour Clinical: Applications within Translational Science

Webinars

Modeling Synergistic Anti-PD-1/PD-L1 Immunotherapy Combinations with the Virtual Tumour

Posters

Virtual Tumour Clinical development, part II: translational modelling of vemurafenib, selumetinib and docetaxel in metastatic melanoma

Posters

Modeling the Emergence of Resistance to Chemotherapeutics with Virtual Tumour

Presentations

Translational modelling of vemurafenib, selumetinib and docetaxel in metastatic melanoma with Virtual Tumour Clinical

Presentations

Cancer Modeling and Drug Schedule Optimization

Presentations

Systems Biology for Cancer Drug Development

Presentations

Virtual Tumour Clinical development, part I: translational modelling of docetaxel-thalidomide combination treatment in metastatic, castrate-resistant prostate cancer

Posters

Immunotherapy modelling

Webinars

Cardiotoxicity modelling

Webinars

Virtual Tumour Pre-clinical Technology Webinar

Webinars

Reducing animal experiments with the Virtual Tumour

Posters

Virtual Tumour Clinical: Literature Example

Posters

Predicting Torsades de Pointes (TdeP) risk from data generated via highthroughput screening

Posters

The application of three-dimensional cell cultures in combination with the Virtual Tumor™ for designing optimal drug dosing schedules

Posters

Modeling the sequence-sensitive gemcitabine-docetaxel combination using the Virtual Tumor

Posters

Predicting the effect of combination schedules on xenograft tumor using the Virtual Tumor

Posters

Computer modelling of Nocodazole exposure on cell cultures in vitro

Posters

Optimal cancer chronotherapeutics schedules using a Systems Biology approach – Chronotherapeutics of Seliciclib

Presentations

Optimal cancer chronotherapeutic schedules of Seliciclib revealed by a systems biology approach

Posters

Systems biology analysis of CYC116, a novel aurora kinase inhibitor

Posters

Using a mammalian cell cycle simulation to interpret differential kinase inhibition in anti-tumour pharmaceutical development

Publications

Resources

Explore our Resources Library

Our Science Hub provides you with quick and easy access to all of Physiomics cutting edge research and though leadership, including our latest scientific posters and publications, research papers and webinars.

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