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Our Science Hub provides you with quick and easy access to all of Physiomics cutting edge research and though leadership, including our latest scientific posters and publications, research papers and webinars.

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Posters
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Publications
Webinars

17th April 2025 – A Pharmacokinetic and Pharmacodynamic Model of an IL-12 Anchored-Drug Conjugate for…

Publications

6th February 2025 – Semi-mechanistic efficacy model for PARP + ATR inhibitors…

Publications

14th January 2025 – A Multiple-Model-Informed Drug-Development Approach for Optimal Regimen Selection…

Publications

26th November 2024 – Data analysis and model evaluation of chemotherapy induced neutropenia Results from the PARTNER trial

Posters

7th November 2024 – Physiomics marks record year with expanding consultancy and personalized medicine initiatives

Presentations

16th October 2023 – Preclinical pharmacokinetic (PK) and tumour growth inhibition (TGI) modelling for mANK-101

Posters

9th May 2023 – Should personalised dosing have a role in cancer treatment?

Publications

18th April 2023 – AACR 2023 – Abstract Number: 5699

Presentations

4th April 2023 – Mathematical modelling in the age of Project Optimus

Webinars

30th March 2023 – Mathematical modelling in the age of Project Optimus – slides

Presentations

10th November 2022 – Establishing the preclinical PKPD relationship for NM32-2668 a ROR1 targeting T cell engager

Posters

12th November 2021 – Establishing the translational PK/PD relationship for BT7480, a Nectin-4/CD137 Bicycle TICA

Posters

10th April 2021 – The abscopal effect: modeling and predicting the effect of radiation therapy on non-irradiated tumors when combined with immune-checkpoint blockers

Posters

10th April 2021 – A precision dosing application for patients treated with docetaxel and G-CSF

Posters

22nd June 2020 – Optimizing Dual Immuno-oncology Combinations with a Virtual Tumor

Posters

28th April 2020 – BioTrinity 2020: Modelling in immuno-oncology

Presentations

21st June 2019 – Developing a head and neck cancer model to assess the effect of radiotherapy on tumour growth inhibition and regrowth

Posters

12th May 2019 – Convert Pharmaceuticals Case Study

Case Studies

3rd May 2019 – CellCentric Case Study

Case Studies

30th April 2019 – Physiomics presentation at Biotrinity 2019

Presentations

1st April 2019 – Modelling the effect of Radiotherapy on tumour growth inhibition: the head and neck tumour case head and neck tumour case

Posters

1st April 2019 – A Precision Dosing Application For Advanced Prostate Cancer Chemotherapy

Posters

29th March 2019 – QSP versus the rest: let the competition commence! by Dr Hitesh Mistry

Publications

30th March 2019 – A Decision Support System for the treatment of esophageal cancer

Posters

29th March 2019 – Using Predictive Mathematical Models to Optimise the Scheduling of Anti-Cancer Drugs by David Orrell and Eric Fernandez

Publications

28th March 2019 – Modelling the Emergence of Resistance to Chemotherapeutics with Virtual Tumour

Posters

27th March 2019 – Modelling and translating head and neck radiation therapy on all three levels: in vitro, in vivo and clinical

Posters

26th March 2019 – Virtual Tumour Clinical: Applications within Translational Science

Webinars

25th March 2019 – Modeling Synergistic Anti-PD-1/PD-L1 Immunotherapy Combinations with the Virtual Tumour

Posters

24th March 2019 – Virtual Tumour Clinical development, part II: translational modelling of vemurafenib, selumetinib and docetaxel in metastatic melanoma

Posters

21st March 2019 – Modeling the Emergence of Resistance to Chemotherapeutics with Virtual Tumour

Presentations

20th March 2019 – Translational modelling of vemurafenib, selumetinib and docetaxel in metastatic melanoma with Virtual Tumour Clinical

Presentations

19th March 2019 – Cancer Modeling and Drug Schedule Optimization

Presentations

18th March 2019 – Systems Biology for Cancer Drug Development

Presentations

17th March 2019 – Virtual Tumour Clinical development, part I: translational modelling of docetaxel-thalidomide combination treatment in metastatic, castrate-resistant prostate cancer

Posters

16th March 2019 – Immunotherapy modelling

Webinars

15th March 2019 – Cardiotoxicity modelling

Webinars

14th March 2019 – Virtual Tumour Pre-clinical Technology Webinar

Webinars

13th March 2019 – Reducing animal experiments with the Virtual Tumour

Posters

12th March 2019 – Virtual Tumour Clinical: Literature Example

Posters

11th March 2019 – Predicting Torsades de Pointes (TdeP) risk from data generated via highthroughput screening

Posters

10th March 2019 – The application of three-dimensional cell cultures in combination with the Virtual Tumor™ for designing optimal drug dosing schedules

Posters

Modeling the sequence-sensitive gemcitabine-docetaxel combination using the Virtual Tumor

Posters

Predicting the effect of combination schedules on xenograft tumor using the Virtual Tumor

Posters

Computer modelling of Nocodazole exposure on cell cultures in vitro

Posters

6th March 2019 – Optimal cancer chronotherapeutics schedules using a Systems Biology approach – Chronotherapeutics of Seliciclib

Presentations

Optimal cancer chronotherapeutic schedules of Seliciclib revealed by a systems biology approach

Posters

Systems biology analysis of CYC116, a novel aurora kinase inhibitor

Posters

17th February 2006 – Using a mammalian cell cycle simulation to interpret differential kinase inhibition in anti-tumour pharmaceutical development

Publications