Why Work With Us?
Our services are unique and bespoke, we work with you in agile, collaborative teams to solve real development challenges.
Oncology & Modelling Specialists
Our specialisation in oncology means we offer you deep oncology modelling expertise, helping you save time and money.
Unique Virtual Tumour™ Technology
Virtual Tumour™ is our latest proprietary model-aided simulation to help improve the success rate of drug development.
Industry & Academic Experience
Based in Oxford, our team of experts have accumulated over 120 years of experience across pre-clinical and clinical pharmacology.
Agile Collaborations
Our skilled teams are agile, collaborative and efficient. We work with you to solve real development challenges.
What our partners are saying about us
Nigel Brooks, Cellcentric
We have worked with Physiomics to help provide answers to some critical early clinical development questions with CCS1477, our novel p300/CBP inhibitor. The analysis performed by Physiomics and the interpretation and input from their modelling experts has been invaluable. We now have the comfort that the next steps we are taking with the development of CCS1477 are data driven and validated through expert modelling data. Thanks for all your help.
Phil Jeffrey, Bicycle Therapeutics
Physiomics has provided pk/pd modelling and data analysis expertise on several of our oncology projects. We have found the group to be talented, experienced and committed to delivering high quality results in a timely manner. Physiomics has helped us achieve a more quantitative and translational understanding of our novel molecules.
Our Services
We support all phases of R&D. Our core capabilities include:
PK/PD Modelling
Construct Pharmacokinetic (PK) & Pharmacodynamic (PD) models to evaluate dose response.
Virtual Tumour™ Technology
Virtual Tumour will help you simulate tumours under the effects of any combination of anti-cancer agents.
Quantitative Systems Pharmacology
Create mechanistic models to provide you with valuable insights.
Personalised Oncology
Discover Physiomics’ innovative tool for the personalised treatment of cancer.
Experience the Power of Virtual Tumour™ Technology
Utilise our advanced proprietary technology to help accelerate drug development.
Virtual Tumour™ has been developed and refined based on years of experience in simulating a huge variety of cancer types, targets and drugs.
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Personalised Cancer Treatment
Prostate cancer affects 47,000 men per year in the UK and metastatic disease has less than a 30% 5-yr survival rate.
Physiomics is developing an innovative new Precision Dosing tool for the personalisation of docetaxel treatment of late stage castrate-resistant prostate cancer. If it were to be approved by regulatory authorities, the tool would potentially be able to:
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Case Study
Physiomics is increasingly working with companies at the stage of pre-clinical to clinical translation and has been able to work closely with its clients to provide supporting materials for use with third parties such as regulatory agencies. Here we provide an example from a project where the client was already in Phase 1 for one indication and wanted supporting evidence for dosing in a new indication.
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A Track Record of Success
We have a strong track record of success working with big pharma, research and academia
Reduction in Number of Studies
*Combination case studies have shown that we can save between 8 and 18 groups of mice.
Reduction in Cost and Time
*Optimal combination schedules could be obtained in 3 months instead of 6 or 9 months.
Increased Success Rate
*Predicted improved regimen which was better than expert opinion.
* [Achievements are derived from specific client projects and will vary subject to the project].
70
Projects Completed
90
Targets & Drugs Modelled
120
Years of Combined Experience
122
Publications
Interested in Finding Out More?
Send us your query and we’ll put you in touch with the relevant expert in our team.
